Epitalon: what the evidence actually shows

Epitalon is a synthetic tetrapeptide derived from a pineal gland extract studied in Russian gerontology research.

Also known as epithalon, epithalamin, AEDG.

Evidence and regulatory status

Animal or laboratory evidence only. No published human trial.

Not approved by the FDA or the European Medicines Agency for any indication.

Half-life

No published human pharmacokinetic study reports a half-life for Epitalon. Figures circulating on vendor and forum pages are not traceable to a human trial, so this page does not repeat them.

What published trials used

No published human dosing trial exists for Epitalon.

Reported for reference only. What a trial administered under supervision is not a recommendation, and Gireta does not make one.

How much research exists

PubMed records
142
Tagged human
41
Clinical trials
1

A PubMed search for Epitalon returns 142 records, of which 41 are tagged as human research and 1 is typed as a clinical trial.

Counted on . Counts drift, so the exact query is linked rather than described, and you can re-run it.

Common questions

Is epitalon approved?
No. Epitalon is not approved by the FDA or by the European Medicines Agency for any indication.
Where does the epitalon research come from?
Most of it originates from a single research group and is published in Russian-language or low-circulation journals. One PubMed record is typed as a clinical trial. Independent replication outside that group is limited.
What is the half-life of epitalon?
No published human pharmacokinetic study reports a half-life for epitalon, so this page does not state one.

Sources

  1. Epitalon overview · International Journal of Molecular Sciences, via PubMed, 2025

Related compounds

Others graded preclinical here

Held to the same standard on this site. Each page prints its own literature counts, so where a record is typed as a clinical trial you can see it rather than take our word for the grade.

  • BPC-157 no records typed as a clinical trial
  • TB-500 1 record typed as a clinical trial
  • GHK-Cu 3 records typed as a clinical trial

Planning a schedule?

Gireta turns a compound and a cadence into a twelve-week timeline with the reconstitution maths worked out and a monthly cost.

Plan a Epitalon schedule

Last reviewed .